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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYBL2 All Species: 28.79
Human Site: S472 Identified Species: 48.72
UniProt: P10244 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10244 NP_002457.1 700 78764 S472 T L E L E S P S L T S T P V C
Chimpanzee Pan troglodytes XP_514658 769 86303 S472 T L E L E S P S L T S T P V C
Rhesus Macaque Macaca mulatta XP_001084853 700 78675 S472 T L E L E S P S L T S T P V C
Dog Lupus familis XP_534424 883 97262 S655 T L E L E S P S L T S T P V C
Cat Felis silvestris
Mouse Mus musculus P48972 704 79084 S475 T L E L E S P S L T S T P V C
Rat Rattus norvegicus NP_001100006 704 79549 S476 T L E L E S P S L T S T P V C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511778 753 85883 A508 Q L N L D N P A F T S T P I C
Chicken Gallus gallus Q03237 686 77718 S455 T L E L E N P S L T S T P V C
Frog Xenopus laevis P52551 743 82891 L475 K F A A D H V L H T P T P F K
Zebra Danio Brachydanio rerio NP_001003867 633 70853 E429 K T P L T Q K E N S L F I T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797351 686 76826 R478 F R T P R I R R S L I D T P R
Poplar Tree Populus trichocarpa
Maize Zea mays P20024 340 36221 P136 G S G D A G T P A T A P L S S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7G7 776 86488 S544 L V P L N S F S S P S R V N K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa O13493 324 36522 R120 L R R Q S A P R R V S A S D V
Conservation
Percent
Protein Identity: 100 88 98.2 72.5 N.A. 85.2 87.7 N.A. 38.3 72.5 54.2 52.1 N.A. N.A. N.A. N.A. 37.8
Protein Similarity: 100 89.7 98.7 74.7 N.A. 89.4 91.3 N.A. 54.5 81.5 69 65.8 N.A. N.A. N.A. N.A. 54
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 53.3 93.3 20 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 80 100 26.6 13.3 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. 20.1 N.A. 25.5 N.A. 20.7
Protein Similarity: N.A. 31.8 N.A. 40.8 N.A. 29.5
P-Site Identity: N.A. 6.6 N.A. 26.6 N.A. 13.3
P-Site Similarity: N.A. 13.3 N.A. 33.3 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 8 8 0 8 8 0 8 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 58 % C
% Asp: 0 0 0 8 15 0 0 0 0 0 0 8 0 8 0 % D
% Glu: 0 0 50 0 50 0 0 8 0 0 0 0 0 0 0 % E
% Phe: 8 8 0 0 0 0 8 0 8 0 0 8 0 8 0 % F
% Gly: 8 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 8 0 8 8 0 % I
% Lys: 15 0 0 0 0 0 8 0 0 0 0 0 0 0 15 % K
% Leu: 15 58 0 72 0 0 0 8 50 8 8 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 8 15 0 0 8 0 0 0 0 8 0 % N
% Pro: 0 0 15 8 0 0 65 8 0 8 8 8 65 8 8 % P
% Gln: 8 0 0 8 0 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 15 8 0 8 0 8 15 8 0 0 8 0 0 8 % R
% Ser: 0 8 0 0 8 50 0 58 15 8 72 0 8 8 8 % S
% Thr: 50 8 8 0 8 0 8 0 0 72 0 65 8 8 0 % T
% Val: 0 8 0 0 0 0 8 0 0 8 0 0 8 50 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _